The main indication for the use of EPO is anemia due to chronic renal failure or chemotherapy. Adverse effects of EPO include flu-like symptoms and increase in blood pressure, volume and viscosity. Together with the treatment with EPO, iron suppletion is useful.
Beware of EPO abuse by athletes and cyclists! Hypertension and thrombosis are dangerous complications with the use of EPO, when the hematocrit rises too rapidly.
The route of EPO administration is…
Extra info: Remember that EPO is a protein. So after oral administration it will be broken down by gastro-intestinal enzymes before reaching the circulation.