Dobutamine in shock
Dobutamine is a synthetically derived catecholamine that acts on β1-adrenergic receptors. It is used to increase cardiac contractility in situations where little dilation of the peripheral vasculature is desired.
The combination of increased contractility and decreased afterload is helpful in maintaining cardiac output in patients with a weakened heart. However, due to the decrease in systemic perfusion, it should be used cautiously in hypovolaemic states.
What is TRUE about dobutamine?
Extra info: Dobutamine increases contractility of the heart through β1-receptor stimulation. It is used in cardiogenic and septic shock. It only has mild action on β2- and α1-receptors.