Hyperlipidemia is characterized by increased levels of lipoproteins in the plasma. This disease can be due to a genetic disorder resulting in abnormalities in the lipoprotein metabolism caused by mutations in apoproteins, lipoprotein receptors or lipoprotein lipase. The most common types of hyperlipidemia and their characteristics are depicted in the graphics and discussed below.
Secondary hyperlipidemias can be caused by:
Extra info: Metabolic/endocrine diseases and certain drugs can cause secondary hyperlipidemia. Heart failure, tachycardia and diabetes insipidus are not known to induce secondary hyperlipidemia.
Which of the following is the primary defect in familial hypercholesterolemia?