last updated 22-10-2021

Neuronal network: GABA inhibition

Neuronal network control GABA inhibition

In a physiological neuronal network, action potentials do normally not generate a seizure. As seen in the graphic, action potentials are generated by an excitatory neuron. This neuron excitates other excitatory neurons and inhibitory GABA-interneurons. The GABA-neurons transmit inhibitory signals to their surrounding cells. These processes within in the neuronal network result in amplification of

local signals but also in reduction of the signal transmission and protection against synchronicity. In other words: the GABA inhibitory neurons keep the excitation within control.
Seizures are a result of a misbalance between the excitatory signals and inhibitory control.

1

What is not true about the GABA-A receptor complex? 

2

With regard to GABA, which of the following is INCORRECT? GABA…

3

Epilepsy is a condition with a periodic recurrence of seizures with or without convulsions. 

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