Acetylcholine transporter reuptake is the most efficient mechanism for clearing the synapse of released acetylcholine.
Extra info: Unfortunately, there is no reuptake transporter the acetylcholine neurotransmitter. However, there is a transporter for the choline that results from acetylcholinesterase metabolism.
Which of the following is true regarding nicotinic receptors?
Extra info: Ligand gated ion-channels (such as nicotinic receptors) are less responsive to receptor regulation and as such are said to lack “plasticity”. A is wrong because nicotine does cross the BBB. C is wrong because ion-channels respond quicker to an agonist than G-protein receptors. D is wrong because acetylcholine is the primary agonist.
The nicotinic receptor is a ligand-gated chloride ion channel.
Extra info: Close It is ligand gated SODIUM ion channel.
The choline by product is transported back into the presynaptic neuron for synthesis into acetylcholine.