Microtubule synthesis inhibitors

Mebendazole and albendazole distort the microtubules of intestinal and tegmental cells in the worm. By this action the worm is not able to take up low molecular weight nutrients like glucose anymore and will die.

Microtubule synthesis inhibitors are drug of choice in ascariasis and trichuriasis.


Mebendazole is used in the treatment of cestodes


The oxyuriasis of a pregnant woman should immediately be treated with mebendazole in order to protect the embryo from infection.