Effect of leukotriene modifiers
Leukotriene modifying agents
Leukotrienes are important mediators of the asthmatic inflammatory response. Agents that antagonize their action or inhibit their production can reduce inflammation. However these agents have shown a beneficial clinical effect in only a minority of patients.
Leukotriene modifiers can reduce submucosal edema.
Extra info: One of the major inflammatory actions of leukotrienes is the creation of submucosal edema, therefore it will be reduced when this action is blocked.
Leukotriene modifiers are best used in acute asthma attacks.
Extra info: Leukotriene modifiers are only effective in reducing late inflammatory responses.