Glycopeptides are high molecular weight drugs consisting of protein and sugar. By binding to the carboxyl end of the pentapeptide, they sterically block the attachment to the peptidoglycan network. This disruption in the cell wall enables water to enter the
Glycopeptides are commonly used against Gram-negative bacteria.
Extra info: Gram-positive bacteria are the targets for glycopeptides like vancomycin.
Glycopeptides are bactericidal.