Drug regimen determination
If a drug company knows the average volume of distribution, clearance and the desired therapeutic range of a particular drug in a particular patient population, it is possible to determine an empiric dosage regimen. The suggested dosages in any therapeutic book are based on this process. Sometimes our patients don’t respond like the average patient and therefore the clinician should be able to determine an appropriate drug regimen for the patient. The concepts involved in giving a single intravenous dose (versus oral), and an intravenous infusion (versus multiple oral doses) will be demonstrated in the next few topics.