Isoprenaline in shock

Isoprenaline

Isoproterenol/isoprenaline is a β1 and β2adrenergic agonist that is also used in the treatment of shock.

This agent acts to increase the heart rate and contractility in order to improve cardiac output, while also causing an increase in peripheral vascular resistance.

This drug is often an agent of last resort in situations when patients have poor tissue perfusion despite other drug therapy. Isoproterenol's β2 adrenergic activity in the lungs suggests that it might be beneficial for oxygenation, but this effect is in fact clinically negligible.

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Which of the following statements about isoprenaline is FALSE?