Mucus is produced mainly by the submucosal glands of cartilaginous airways (off-whiteforms on graphic), and to some extent by the goblet cells in the airway epithelium. Mucus hyper-secretion can be caused by:
- Chronic airway irritation
- Sterile inflammation such as asthma
Mucus and lymphocytes can be present in infectious and non-infectious airways.
Extra info: Mucus and lymphocytes are always present as a part of the host's natural defense system.
Most airway mucus is produced in submucosal glands.
Extra info: Although also produced by the airway globlet cells, the majority of mucus comes from submucosal glands.