TRC: Diabetes mellitus type I

Diabetes mellitus type I

In diabetes mellitus type I, there is an absolute shortage of insulin resulting from autoimmune destruction of pancreatic β-cells. Due to this insulin deficiency, the mechanisms that decrease glucose levels in the blood do not work. As a result, dangerously high blood glucose levels occur, whereas glucose levels in cells are low.

Because DM type I patients cannot even produce modest amounts of insulin, dangerous ketone bodies are formed by fat breakdown and ketoacidosis can occur. Symptoms of diabetic patients are polyuria, dehydration, fatigue, muscle weakness and coma.

I. Treatment with insulin is able to perfectly mimic normal glucose levels.

II. Patients with diabetes type 1 must try to lose weight, before they are treated with insulin.

Extra info: Insulin treatment will never perfectly mimic the normal human insulin secretion. Hyperglycemia will not decrease in type I diabetics by weight loss, because there is an absolute shortage of insulin secretion.

Option explanation:

I is true, II is false

I is true, II is true

I is false, II is false

I is false, II is true

Diabetes mellitus type I

Diabetes mellitus type I

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