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    Gram positive and negative

    The cell walls of bacteria are essential for their growth and survival. Peptidoglycans are an essential component of the cell wall, which provide a rigid mechanical stability by a cross-linked network.

    Gram-positive bacteria the cell wall consists of one membrane surrounded by a peptidoglycan layer of 50-100 molecules thick. Gram-negative bacteria only possess a thin layer (1-2 molecules) of peptidoglycans between two membranes. The outer membrane is protected by lipids with an attached sugar chain (lipopolysaccharides).

    1

    Drugs that act on the cell wall are bacteriocidal. 

    2

    The outer membrane in Gram-positive bacteria forms an additional obstacle to the entry of antibiotics. 

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