Adrenergic α1 antagonists

Adrenergic α1 antagonists

Adrenergic α1-receptor antagonists block the action of (nor)adrenalin. These drugs bind the α1-receptor, decrease vasoconstriction and thus decrease blood pressure. α1-antagonists are prescribed to treat hypertension and can also treat hypertension caused by pheochromocytoma. Doxazosin

and prazosin belong to this group of drugs.

For more information, see α-receptor blockers in the cardiology section.


A pheochromocytoma can be surgically removed prior to α and β-block.