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    Paroxysmal depolarising shift

    Seizures are initiated by abnormal depolarisations in a neuron or group of neurons. The paroxysmal depolarising shift is a sudden abnormal depolarisation which is characterized by a train of action potentials.

    So in contrast to the normal physiological situation in which the sodium channel is inactivated during the repolarisation, now the channels are still activated generating a number of depolarisations.

    1

    Which of the following is NOT commonly associated with neuronal membrane instability? 

    2

    For an action potential to begin, an area of excitable membrane must

    3

    During the absolute refractory period, the membrane