Neuronal network dysregulation Partial seizures
With partial seizures, the focus is most often localized in the frontal or temporal region and the seizure remains within the hemisphere.
The seizure starts with increased electrical activity in a single excitatory neuron. This sudden depolarisation is called a paroxysmal depolarizing
Normal neuronal activity depends on adequate concentrations of all the following EXCEPT:
Extra info: The inhibitory neurotransmitter GABA needs to be present to counteract the excitatory stimulation, and if there isn’t enough sodium or glucose, seizures can occur in a normal patient. Antiepileptics are only necessary to maintain normal neuronal activity in diseased patients.