Afterload

Afterload

Afterload is the tension in the ventricular wall that is generated during ventricular systolic ejection. This tension is determined by the sum of forces preventing ejection of blood from the ventricle. Afterload can be increased by several factors, all having to do with a decrease in ventricular outflow tract resistance and/or arterial vascular resistance:

Afterload can also be decreased by:

When afterload increases, there is an increase in end-systolic volume and a decrease in stroke volume,