Non-steroid receptors
Thyroid hormone receptor (TR), vitamin D receptor, retinoic acid receptor (RAR), peroxisome proliferator-activated receptor (PPAR), and liver oxysterol receptor (LXR) are examples of receptors belonging to the nuclear receptor subgroup type II. These receptors are always localized in the nucleus regardless of the ligand binding status.
In contrast to the steroid receptors, they bind DNA as heterodimers, usually with
Other receptors from this group bind lipids, prostaglandins, non-steroidal drugs, fibrates and thiazolidinediones.