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    Diarrhoea

    In this picture, the causative factors for diarrhoea are shown. Common physiological factors include:

    1. Over-stimulation of the parasympathetic system
    2. Inhibition of the sympathetic system
    3. Presence of bacteria or viruses
    4. Over-secretion of water and electrolytes secondary to gastrointestinal irritation

    These physiological effects can arise from co-morbid disease states and/or concomitant drug use. However, since the most common aetiologies are self-limiting, drug therapy is rarely indicated. In severe cases or in cases involving paediatric or elderly patients, oral rehydration therapy should be initiated.

    1

    I. Therapy that decreases GI motility is indicated in patients with diarrhoea due to Salmonella

    II. Prolonged diarrhoea will lead to potassium depletion