Urge incontinence describes the situation in which urine is lost because of serious involuntary contractions of the bladder. In motor urge incontinence, the detrusor is overactive and contractions are spontaneous. This can be accompanied by relaxation of the sphincters. In sensory urge incontinence, the afferent signalling is overactive, leading to increased urgency to urinate.
Detrusor overactivity can be caused by neurological disorders, sedating drugs and bladder infection. Also unexpected high urine production due to the use of diuretics can result in incontinence.
Treatment of urge incontinence usually begins with bladder training aiming at increase of the capacity of the bladder. If this is not effective, pharmacological treatment aimed at decreasing the detrusor activity can be applied.
Which is the most commonly used drug for the treatment of motor urge incontinence?
Extra info: The best treatment of urge incontinence is an anticholinergic. However, you need to avoid the cardiac effects that would be present with the use of atropine, therefore oxybutynin.