Benigne erostate hyperplasia
Hyperplasia of the prostate gland is a common phenomenon in elderly men. Prostate hyperplasia is a benign proliferative disorder which causes continence problems such as hesitancy, intermittent voiding, a diminished stream, incomplete emptying, and postvoid leakage, and repeated urinary tract infections. When the prostate becomes so large that the urethra is blocked completely, urine retention will occur.
Verdana, Arial; text-size-adjust: auto; background-color: #e4eaff;" />Pharmacological treatment of prostate hyperplasia is aimed at diminishing the size of the prostate and/or decrease sphincter tone with α1-antagonists. Indications for surgery are urine retention, repeated infections and a lack of response after drug treatment. Large prostates are not automatically surgically removed and small prostates sometimes need surgery.
Prostate hyperplasia causes difficulties with urination, such as
Extra info: Since the outflow of the urine is blocked (retention), emptying is often not complete, leading to frequency and urgency symptoms.
I Muscarinic receptor antagonists can directly increase urine retention in case of prostate hyperplasia. II Calcium antagonists relieve urinary problems in case of prostate hyperplasia.
Extra info: Although muscarinic antagonists will not cause a direct worsening of the outflow obstruction, they will decrease detrusor activity and worsen the symptoms of incontinence. Calcium antagonists are not used in the treatment of prostate hyperplasia, but α1-antagonists are.