Synthetic vasopressin or desmopressin has a stronger and more prolonged action in comparison with natural vasopressin. Vasopressin binds to the V2 receptor in tubular cells. This leads
Intranasal administration, intravenous administration or oral administrations are possible routes of administration in diabetes insipidus.
Overdosage over desmopressin (=vasopressin/ADH) does NOT exist.
Extra info: Overdosage of desmopressin can result in severe water intoxication (decreased sodium levels, cramps, increased weight).