Carbonic anhydrase inhibitors
Carbonic anhydrase inhibitors in glaucoma
The carbonic anhydrase inhibitor acetazolamide is administered systemically. In the eye, this drug inhibits the enzyme carbonic anhydrase, which ultimately decreases the aqueous humour production by reducing the formation of carbonic acid (and therefore bicarbonate). Systemically, this drug acts as a diuretic and causes side effects such as paresthesia, hypokalaemia, lack of appetite, drowsiness, and depression.